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What are SARMs?

What are SARMs?

Selective Androgen Receptor Modulators (SARMs) are a class of therapeutic

compounds that have similar anabolic properties to anabolic steroids, but with

reduced androgenic (producing male characteristics) properties. As an example, the

androgen receptor is activated by binding androgens, such as testosterone. Unlike

anabolic steroids, which bind to androgen receptors in many tissues all over the

body, individual SARMs selectively bind androgen receptors in certain tissues, but not

in others.

In medical settings, this could be very useful for stimulating specific tissue growth

like muscle and bone, while avoiding unwanted side effects in other tissues like the

liver or skin. SARMs are being evaluated as a clinical treatment for muscle-wasting

caused by several diseases, such as osteoporosis, cancer, heart failure, chronic

obstructive pulmonary disease, end-stage liver disease, end-stage renal disease, and

HIV. To date, all SARMs are for investigational purposes only.

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Are SARMs prohibited on the World Anti-Doping

Agency (WADA) Prohibited List?

All SARMs are prohibited at all times (both in and out-of-competition) for all athletes,

from those competing at the highest level of sport to those competing at the

recreational level. SARMs are listed in the category of “Other Anabolic Agents” under

section S1.2 of the WADA Prohibited List.

Examples of SARMs include: ostarine (Enobosarm, MK 2866), andarine, LGD-4033

(ligandrol), and RAD140.[3] SARMs have the potential to be misused for

performance enhancement in sport due to their anabolic properties, as well as their

ability to stimulate androgen receptors in muscle and bone, leading to bone and

muscle growth.

Therefore, if you want to use such products, please check whether the local laws and

your location can be reasonably applied

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